| Address: | 4000 Rsrvoir Rd Bldg D395, Washington, DC 20057, USA |
|---|---|
| Postal code: | 20057 |
| Phone: | (202) 687-4082 |
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Introduction. Angiotensin II generates reactive oxygen species (ROS) by activation of angiotensin II type 1 receptors (AT 1-R).The resulting ROS mediates many of the actions of Ang II, including constriction of vascular smooth muscles, increased systemic blood pressure, endothelial dysfunction, vascular remodeling and sodium retention.